Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

The spread of multiple myeloma (MM) involves (re)circulation into the peripheral blood and (re)entrance or homing of MM cells into new sites of the BM. Hypoxia in solid tumors was shown to promote metastasis through activation of proteins involved in the epithelial-mesenchymal transition (EMT) proce...

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Detalhes bibliográficos
Main Authors: Azab, Abdel Kareem, Hu, Jinsong, Quang, Phong, Azab, Feda, Pitsillides, Costas, Awwad, Rana, Thompson, Brian, Maiso, Patricia, Sun, Jessica D., Hart, Charles P., Roccaro, Aldo M., Sacco, Antonio, Ngo, Hai T., Lin, Charles P., Kung, Andrew L., Carrasco, Ruben D., Vanderkerken, Karin, Ghobrial, Irene M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382938/
https://ncbi.nlm.nih.gov/pubmed/22394600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-380410
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