Dual Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Blockade Produces THC-Like Morris Water Maze Deficits in Mice

[Image: see text] Acute administration of Δ(9)-tetrahydrocannabinol (THC) or exposure to marijuana smoke impairs short-term spatial memory in water maze tasks through a CB(1) receptor mechanism of action. N-Arachidonoylethanolamine (anandamide; AEA) and 2-arachidonoylglycerol (2-AG) are endogenous c...

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Bibliographic Details
Main Authors: Wise, Laura E., Long, Kelly A., Abdullah, Rehab A., Long, Jonathan Z., Cravatt, Benjamin F., Lichtman, Aron H.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2012
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382457/
https://ncbi.nlm.nih.gov/pubmed/22860205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200130s
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