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Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE(2)
PGE(2), produced in the lung during infection with microbes such as Klebsiella pneumoniae, inhibits alveolar macrophage (AM) antimicrobial functions by preventing H(2)O(2) production by NADPH oxidase (NADPHox). Activation of the NADPHox complex is poorly understood in AMs, although in neutrophils it...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382311/ https://ncbi.nlm.nih.gov/pubmed/22544939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1211590 |
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