EP4 and EP2 receptor activation of protein kinase A by prostaglandin E(2) impairs macrophage phagocytosis of Clostridium sordellii

PROBLEM: Clostridium sordellii causes endometrial infections but little is known regarding host defenses against this pathogen. METHOD OF STUDY: We tested the hypothesis that the immunoregulatory lipid prostaglandin (PG) E(2) suppresses human macrophage clearance of C. sordellii through receptor-ind...

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Detalhes bibliográficos
Main Authors: Rogers, Lisa M., Thelen, Tennille, Fordyce, Krystle, Bourdonnay, Emilie, Lewis, Casey, Yu, Han, Zhang, Junyong, Xie, Jingli, Serezani, Carlos H., Peters-Golden, Marc, Aronoff, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864121/
https://ncbi.nlm.nih.gov/pubmed/23902376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12153
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