Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase

Leukotrienes (LTs) are lipid mediators that participate in inflammatory diseases and innate immune function. We sought to investigate the importance of LTs in regulating the microbicidal activity of alveolar macrophages (AMs) and the molecular mechanisms by which this occurs. The role of LTs in enha...

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Detalhes bibliográficos
Main Authors: Serezani, Carlos H. C., Aronoff, David M., Jancar, Sonia, Mancuso, Peter, Peters-Golden, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Phagocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895163/
https://ncbi.nlm.nih.gov/pubmed/15718414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-08-3323
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