Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase

Leukotrienes (LTs) are lipid mediators that participate in inflammatory diseases and innate immune function. We sought to investigate the importance of LTs in regulating the microbicidal activity of alveolar macrophages (AMs) and the molecular mechanisms by which this occurs. The role of LTs in enha...

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Main Authors: Serezani, Carlos H. C., Aronoff, David M., Jancar, Sonia, Mancuso, Peter, Peters-Golden, Marc
格式: Artigo
語言:Inglês
出版: © 2005 by The American Society of Hematology 2005
主題:
Phagocytes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895163/
https://ncbi.nlm.nih.gov/pubmed/15718414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-08-3323
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