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Leukotriene B(4) amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression
Activation of NF-κB and 5-lipoxygenase–mediated (5-LO–mediated) biosynthesis of the lipid mediator leukotriene B(4) (LTB(4)) are pivotal components of host defense and inflammatory responses. However, the role of LTB(4) in mediating innate immune responses elicited by specific TLR ligands and cytoki...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026722/ https://ncbi.nlm.nih.gov/pubmed/21206089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43302 |
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