Comparative Processing and Function of Human and Ferret Cystic Fibrosis Transmembrane Conductance Regulator

The most common cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation is ΔF508, and this causes cystic fibrosis (CF). New CF models in the pig and ferret have been generated that develop lung, pancreatic, liver, and intestinal pathologies that reflect disease in CF patients. Speci...

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Detalhes bibliográficos
Main Authors: Fisher, John T., Liu, Xiaoming, Yan, Ziying, Luo, Meihui, Zhang, Yulong, Zhou, Weihong, Lee, Ben J., Song, Yi, Guo, Chenhong, Wang, Yujiong, Lukacs, Gergely L., Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381131/
https://ncbi.nlm.nih.gov/pubmed/22570484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336537
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