Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination

TAR DNA-binding protein 43 (TDP-43) is a major component within ubiquitin-positive inclusions of a number of neurodegenerative diseases that increasingly are considered as TDP-43 proteinopathies. Identities of other inclusion proteins associated with TDP-43 aggregation remain poorly defined. In this...

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Main Authors: Dammer, Eric B., Fallini, Claudia, Gozal, Yair M., Duong, Duc M., Rossoll, Wilfried, Xu, Ping, Lah, James J., Levey, Allan I., Peng, Junmin, Bassell, Gary J., Seyfried, Nicholas T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380899/
https://ncbi.nlm.nih.gov/pubmed/22761693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038658
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