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Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Gene duplication is a powerful driver of evolution. Newly duplicated genes acquire new roles that are relevant to fitness, or they will be lost over time. A potential path to functional relevance is mutation of the coding sequence leading to the acquisition of novel biochemical properties, as analyz...

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Autors principals: Bochkis, Irina M., Schug, Jonathan, Ye, Diana Z., Kurinna, Svitlana, Stratton, Sabrina A., Barton, Michelle C., Kaestner, Klaus H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380847/
https://ncbi.nlm.nih.gov/pubmed/22737085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002770
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