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Impaired male fertility and atrophy of seminiferous tubules caused by haploinsufficiency for Foxa3

Foxa1, 2 and 3 (formerly HNF-3α, -β and -γ) constitute a sub-family of winged helix transcription factors with multiple roles in mammalian organ development. While all three Foxa mRNAs are present in endoderm derivatives including liver and pancreas, only Foxa3 is expressed in the testis. Here we de...

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Bibliographische Detailangaben
Hauptverfasser: Behr, Rüdiger, Sackett, Sara D., Bochkis, Irina M., Le, Phillip Phuc, Kaestner, Klaus H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952241/
https://ncbi.nlm.nih.gov/pubmed/17488644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.03.525
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