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Bile acid-induced inflammatory signaling in mice lacking Foxa2 in the liver leads to activation of mTOR and age-onset obesity()

Cytokine signaling has been connected to regulation of metabolism and energy balance. Numerous cytokine gene expression changes are stimulated by accumulation of bile acids in livers of young Foxa2 liver-conditional null mice. We hypothesized that bile acid-induced inflammation in young Foxa2 mutant...

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Detalhes bibliográficos
Main Authors: Bochkis, Irina Mikhailovna, Shin, Soona, Kaestner, Klaus Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855091/
https://ncbi.nlm.nih.gov/pubmed/24327960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.08.005
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