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Foxa2-dependent hepatic gene regulatory networks depend on physiological state
Bile acids are powerful detergents produced by the liver to aid in the absorption of dietary lipids. We recently reported a novel role for Foxa2 in bile acid metabolism. The winged helix transcription factor Foxa2 is required to prevent intrahepatic cholestasis and liver injury in mice fed a cholic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712224/ https://ncbi.nlm.nih.gov/pubmed/19417011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90376.2008 |
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