Carregant...

Continual low-level MEK inhibition ameliorates cardio-facio-cutaneous phenotypes in zebrafish

Cardio-facio-cutaneous (CFC) syndrome is caused by germline mutations in KRAS, BRAF and MEK1/2. The highly selective and potent MEK inhibitors that have been developed as anti-cancer agents hold potential as therapeutics for CFC syndrome. We have previously shown that the effects of CFC mutations on...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Anastasaki, Corina, Rauen, Katherine A., Patton, E. Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380717/
https://ncbi.nlm.nih.gov/pubmed/22301711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008672
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!