Yüklüyor......

Kinase-activating and kinase-impaired cardio-facio-cutaneous syndrome alleles have activity during zebrafish development and are sensitive to small molecule inhibitors

The Ras/MAPK pathway is critical for human development and plays a central role in the formation and progression of most cancers. Children born with germ-line mutations in BRAF, MEK1 or MEK2 develop cardio-facio-cutaneous (CFC) syndrome, an autosomal dominant syndrome characterized by a distinctive...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Anastasaki, Corina, Estep, Anne L., Marais, Richard, Rauen, Katherine A., Patton, E. Elizabeth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701326/
https://ncbi.nlm.nih.gov/pubmed/19376813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp186
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!