Mek1(Y130C) mice recapitulate aspects of human cardio-facio-cutaneous syndrome

The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members of the RAS/MAPK pathway also cause severe developmental syndromes collectively known as RASopa...

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Enregistré dans:
Détails bibliographiques
Publié dans:Dis Model Mech
Auteurs principaux: Aoidi, Rifdat, Houde, Nicolas, Landry-Truchon, Kim, Holter, Michael, Jacquet, Kevin, Charron, Louis, Krishnaswami, Suguna Rani, Yu, Benjamin D., Rauen, Katherine A., Bisson, Nicolas, Newbern, Jason, Charron, Jean
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897723/
https://ncbi.nlm.nih.gov/pubmed/29590634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031278
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