Mek1(Y130C) mice recapitulate aspects of human cardio-facio-cutaneous syndrome

The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members of the RAS/MAPK pathway also cause severe developmental syndromes collectively known as RASopa...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Aoidi, Rifdat, Houde, Nicolas, Landry-Truchon, Kim, Holter, Michael, Jacquet, Kevin, Charron, Louis, Krishnaswami, Suguna Rani, Yu, Benjamin D., Rauen, Katherine A., Bisson, Nicolas, Newbern, Jason, Charron, Jean
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897723/
https://ncbi.nlm.nih.gov/pubmed/29590634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031278
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