Mek1(Y130C) mice recapitulate aspects of human cardio-facio-cutaneous syndrome

The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members of the RAS/MAPK pathway also cause severe developmental syndromes collectively known as RASopa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dis Model Mech
Prif Awduron: Aoidi, Rifdat, Houde, Nicolas, Landry-Truchon, Kim, Holter, Michael, Jacquet, Kevin, Charron, Louis, Krishnaswami, Suguna Rani, Yu, Benjamin D., Rauen, Katherine A., Bisson, Nicolas, Newbern, Jason, Charron, Jean
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897723/
https://ncbi.nlm.nih.gov/pubmed/29590634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031278
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