Cargando...
Continual low-level MEK inhibition ameliorates cardio-facio-cutaneous phenotypes in zebrafish
Cardio-facio-cutaneous (CFC) syndrome is caused by germline mutations in KRAS, BRAF and MEK1/2. The highly selective and potent MEK inhibitors that have been developed as anti-cancer agents hold potential as therapeutics for CFC syndrome. We have previously shown that the effects of CFC mutations on...
Gardado en:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists Limited
2012
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380717/ https://ncbi.nlm.nih.gov/pubmed/22301711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008672 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|