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Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where

Accumulation of senile plaques consisting of amyloid-β peptide (Aβ) aggregates is a prominent pathological feature in Alzheimer’s disease. Effective clearance of Aβ from the brain parenchyma is thought to regulate the development and progression of the disease. Macrophages in the brain play an impor...

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Detalles Bibliográficos
Main Authors: Lai, Aaron Y, McLaurin, JoAnne
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380064/
https://ncbi.nlm.nih.gov/pubmed/22737039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.12.6
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