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Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where

Accumulation of senile plaques consisting of amyloid-β peptide (Aβ) aggregates is a prominent pathological feature in Alzheimer’s disease. Effective clearance of Aβ from the brain parenchyma is thought to regulate the development and progression of the disease. Macrophages in the brain play an impor...

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書目詳細資料
Main Authors: Lai, Aaron Y, McLaurin, JoAnne
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380064/
https://ncbi.nlm.nih.gov/pubmed/22737039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.12.6
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