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Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding

BACKGROUND: Aggregation of the amyloid peptides, Aβ40 and Aβ42, is known to be involved in the pathology of Alzheimer's disease (AD). Here we investigate the relationship between peptide aggregation and cell surface binding of three forms of Aβ (Aβ40, Aβ42, and an Aβ mutant). RESULTS: Using con...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bateman, David A, McLaurin, JoAnne, Chakrabartty, Avijit
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871596/
https://ncbi.nlm.nih.gov/pubmed/17475015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-29
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