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Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where

Accumulation of senile plaques consisting of amyloid-β peptide (Aβ) aggregates is a prominent pathological feature in Alzheimer’s disease. Effective clearance of Aβ from the brain parenchyma is thought to regulate the development and progression of the disease. Macrophages in the brain play an impor...

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Bibliografske podrobnosti
Main Authors: Lai, Aaron Y, McLaurin, JoAnne
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380064/
https://ncbi.nlm.nih.gov/pubmed/22737039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.12.6
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