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Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where
Accumulation of senile plaques consisting of amyloid-β peptide (Aβ) aggregates is a prominent pathological feature in Alzheimer’s disease. Effective clearance of Aβ from the brain parenchyma is thought to regulate the development and progression of the disease. Macrophages in the brain play an impor...
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Main Authors: | , |
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Format: | Artigo |
Jezik: | Inglês |
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2012
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380064/ https://ncbi.nlm.nih.gov/pubmed/22737039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.12.6 |
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