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Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where

Accumulation of senile plaques consisting of amyloid-β peptide (Aβ) aggregates is a prominent pathological feature in Alzheimer’s disease. Effective clearance of Aβ from the brain parenchyma is thought to regulate the development and progression of the disease. Macrophages in the brain play an impor...

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Autors principals: Lai, Aaron Y, McLaurin, JoAnne
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380064/
https://ncbi.nlm.nih.gov/pubmed/22737039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl.12.6
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