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Intrinsic Nucleic Acid Dynamics Modulates HIV-1 Nucleocapsid Protein Binding to Its Targets

HIV-1 nucleocapsid protein (NC) is involved in the rearrangement of nucleic acids occurring in key steps of reverse transcription. The protein, through its two zinc fingers, interacts preferentially with unpaired guanines in single-stranded sequences. In mini-cTAR stem-loop, which corresponds to the...

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Main Authors: Bazzi, Ali, Zargarian, Loussiné, Chaminade, Françoise, De Rocquigny, Hugues, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380039/
https://ncbi.nlm.nih.gov/pubmed/22745685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038905
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