Structural determinants of TAR RNA-DNA annealing in the absence and presence of HIV-1 nucleocapsid protein

Annealing of the TAR RNA hairpin to the cTAR DNA hairpin is required for the minus-strand transfer step of HIV-1 reverse transcription. HIV-1 nucleocapsid protein (NC) plays a crucial role by facilitating annealing of the complementary hairpins. To gain insight into the mechanism of NC-mediated TAR...

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Detalles Bibliográficos
Autores principales: Kanevsky, Igor, Chaminade, Françoise, Chen, Yingying, Godet, Julien, René, Brigitte, Darlix, Jean-Luc, Mély, Yves, Mauffret, Olivier, Fossé, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185427/
https://ncbi.nlm.nih.gov/pubmed/21724607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr526
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