Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC

An essential step of the reverse transcription of the HIV-1 genome is the first strand transfer that requires the annealing of the TAR RNA hairpin to the cTAR DNA hairpin. HIV-1 nucleocapsid protein (NC) plays a crucial role by facilitating annealing of the complementary hairpins. Using nuclear magn...

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Detalhes bibliográficos
Main Authors: Bazzi, Ali, Zargarian, Loussiné, Chaminade, Françoise, Boudier, Christian, De Rocquigny, Hughes, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089453/
https://ncbi.nlm.nih.gov/pubmed/21227929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1290
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