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Intrinsic Nucleic Acid Dynamics Modulates HIV-1 Nucleocapsid Protein Binding to Its Targets

HIV-1 nucleocapsid protein (NC) is involved in the rearrangement of nucleic acids occurring in key steps of reverse transcription. The protein, through its two zinc fingers, interacts preferentially with unpaired guanines in single-stranded sequences. In mini-cTAR stem-loop, which corresponds to the...

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Detalhes bibliográficos
Main Authors: Bazzi, Ali, Zargarian, Loussiné, Chaminade, Françoise, De Rocquigny, Hugues, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380039/
https://ncbi.nlm.nih.gov/pubmed/22745685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038905
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