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Insights into the mechanisms of RNA secondary structure destabilization by the HIV-1 nucleocapsid protein

The mature HIV-1 nucleocapsid protein NCp7 (NC) plays a key role in reverse transcription facilitating the two obligatory strand transfers. Several properties contribute to its efficient chaperon activity: preferential binding to single-stranded regions, nucleic acid aggregation, helix destabilizati...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Belfetmi, Anissa, Zargarian, Loussiné, Tisné, Carine, Sleiman, Dona, Morellet, Nelly, Lescop, Ewen, Maskri, Ouerdia, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793207/
https://ncbi.nlm.nih.gov/pubmed/26826129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.054445.115
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