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Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse

Insulin is secreted from the islets of Langerhans in coordinated pulses. These pulses are thought to lead to plasma insulin oscillations, which are putatively more effective in lowering blood glucose than continuous levels of insulin. Gap-junction coupling of β-cells by connexin-36 coordinates intra...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Head, W. Steven, Orseth, Meredith L., Nunemaker, Craig S., Satin, Leslie S., Piston, David W., Benninger, Richard K.P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Diabetes Association 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379660/
https://ncbi.nlm.nih.gov/pubmed/22511206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1312
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