Gap junctions and other mechanisms of cell–cell communication regulate basal insulin secretion in the pancreatic islet

ABSTRACT: Cell–cell communication in the islet of Langerhans is important for the regulation of insulin secretion. Gap-junctions coordinate oscillations in intracellular free-calcium ([Ca(2+)](i)) and insulin secretion in the islet following elevated glucose. Gap-junctions can also ensure that oscil...

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Detalhes bibliográficos
Main Authors: Benninger, R K P, Head, W Steven, Zhang, Min, Satin, Leslie S, Piston, David W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240884/
https://ncbi.nlm.nih.gov/pubmed/21930600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.218909
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