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Cellular Communication and Heterogeneity in Pancreatic Islet Insulin Secretion Dynamics

Coordinated pulses of electrical activity and insulin secretion are a hallmark of the islet of Langerhans. These coordinated behaviors are lost when β-cells are dissociated, which also leads to increased insulin secretion at low glucose. Islets without gap junctions exhibit asynchronous electrical a...

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Bibliografske podrobnosti
Main Authors: Benninger, Richard K.P., Piston, David W.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112137/
https://ncbi.nlm.nih.gov/pubmed/24679927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.02.005
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