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Cellular Communication and Heterogeneity in Pancreatic Islet Insulin Secretion Dynamics
Coordinated pulses of electrical activity and insulin secretion are a hallmark of the islet of Langerhans. These coordinated behaviors are lost when β-cells are dissociated, which also leads to increased insulin secretion at low glucose. Islets without gap junctions exhibit asynchronous electrical a...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112137/ https://ncbi.nlm.nih.gov/pubmed/24679927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.02.005 |
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