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Cell-Intrinsic Functional Effects of the α-Cardiac Myosin Arg-403-Gln Mutation in Familial Hypertrophic Cardiomyopathy

Human familial hypertrophic cardiomyopathy is the most common Mendelian cardiovascular disease worldwide. Among the most severe presentations of the disease are those in families heterozygous for the mutation R403Q in β-cardiac myosin. Mice heterozygous for this mutation in the α-cardiac myosin isof...

詳細記述

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書誌詳細
主要な著者: Chuan, Peiying, Sivaramakrishnan, Sivaraj, Ashley, Euan A., Spudich, James A.
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379014/
https://ncbi.nlm.nih.gov/pubmed/22735528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.049
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