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Expression and purification of active mouse and human NEIL3 proteins

Endonuclease VIII-like 3 (Neil3) is one of the five DNA glycosylases found in mammals that recognize and remove oxidized bases, and initiate the Base Excision Repair (BER) pathway. Previous attempts to express and purify the mouse and human orthologs of Neil3 in their active form have not been succe...

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Main Authors: Liu, Minmin, Bandaru, Viswanath, Holmes, Alicia, Averill, April M., Cannan, Wendy, Wallace, Susan S.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378769/
https://ncbi.nlm.nih.gov/pubmed/22569481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2012.04.022
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