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Expression and purification of active mouse and human NEIL3 proteins

Endonuclease VIII-like 3 (Neil3) is one of the five DNA glycosylases found in mammals that recognize and remove oxidized bases, and initiate the Base Excision Repair (BER) pathway. Previous attempts to express and purify the mouse and human orthologs of Neil3 in their active form have not been succe...

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Detalhes bibliográficos
Main Authors: Liu, Minmin, Bandaru, Viswanath, Holmes, Alicia, Averill, April M., Cannan, Wendy, Wallace, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378769/
https://ncbi.nlm.nih.gov/pubmed/22569481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2012.04.022
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