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Expression and purification of active mouse and human NEIL3 proteins

Endonuclease VIII-like 3 (Neil3) is one of the five DNA glycosylases found in mammals that recognize and remove oxidized bases, and initiate the Base Excision Repair (BER) pathway. Previous attempts to express and purify the mouse and human orthologs of Neil3 in their active form have not been succe...

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Autori principali: Liu, Minmin, Bandaru, Viswanath, Holmes, Alicia, Averill, April M., Cannan, Wendy, Wallace, Susan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378769/
https://ncbi.nlm.nih.gov/pubmed/22569481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2012.04.022
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