Structural characterization of a mouse ortholog of human NEIL3 with a marked preference for single-stranded DNA

Endonuclease VIII-like 3 (Neil3) is a DNA glycosylase of the base excision repair pathway which protects cells from oxidative DNA damage by excising a broad spectrum of cytotoxic and mutagenic base lesions. Interestingly Neil3 exhibits an unusual preference for DNA with single-stranded regions. Here...

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Bibliografiske detaljer
Main Authors: Liu, Minmin, Imamura, Kayo, Averill, April M., Wallace, Susan S., Doublié, Sylvie
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856655/
https://ncbi.nlm.nih.gov/pubmed/23313161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.12.008
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