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Structural characterization of a mouse ortholog of human NEIL3 with a marked preference for single-stranded DNA
Endonuclease VIII-like 3 (Neil3) is a DNA glycosylase of the base excision repair pathway which protects cells from oxidative DNA damage by excising a broad spectrum of cytotoxic and mutagenic base lesions. Interestingly Neil3 exhibits an unusual preference for DNA with single-stranded regions. Here...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856655/ https://ncbi.nlm.nih.gov/pubmed/23313161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.12.008 |
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