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The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo
To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base Excision Repair pathway. Three DNA glycosylases have been identified in mammals that are homologous to the Escherichia coli Fpg and Nei proteins...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841873/ https://ncbi.nlm.nih.gov/pubmed/20185759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908307107 |
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