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The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base Excision Repair pathway. Three DNA glycosylases have been identified in mammals that are homologous to the Escherichia coli Fpg and Nei proteins...

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Detalhes bibliográficos
Main Authors: Liu, Minmin, Bandaru, Viswanath, Bond, Jeffrey P., Jaruga, Pawel, Zhao, Xiaobei, Christov, Plamen P., Burrows, Cynthia J., Rizzo, Carmelo J., Dizdaroglu, Miral, Wallace, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841873/
https://ncbi.nlm.nih.gov/pubmed/20185759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908307107
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