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Autophagosome assembly and cargo capture in the distal axon
Autophagy is an essential lysosomal degradation pathway in neurons, yet the basic mechanisms involved are poorly understood. Here, we discuss our recent study in which we define autophagosome dynamics in primary neurons. We find that autophagosomes initiate at the distal tip of the axon in primary n...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378425/ https://ncbi.nlm.nih.gov/pubmed/22617438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20055 |
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