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Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway

Autophagy is an essential degradative pathway in neurons, yetlittle is known about the mechanisms driving this process in highly polarized cells. Here, we use dual-color live-cell imaging to investigate the neuron-specific mechanisms of constitutiveautophagosome biogenesis in primary DRG and hippoca...

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Detalles Bibliográficos
Main Authors: Maday, Sandra, Holzbaur, Erika L. F.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109719/
https://ncbi.nlm.nih.gov/pubmed/25026034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.001
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