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Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway

Autophagy is an essential degradative pathway in neurons, yetlittle is known about the mechanisms driving this process in highly polarized cells. Here, we use dual-color live-cell imaging to investigate the neuron-specific mechanisms of constitutiveautophagosome biogenesis in primary DRG and hippoca...

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Bibliografiske detaljer
Main Authors: Maday, Sandra, Holzbaur, Erika L. F.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109719/
https://ncbi.nlm.nih.gov/pubmed/25026034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.001
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