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Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
Autophagy is an essential cellular degradation pathway in neurons; defects in autophagy are sufficient to induce neurodegeneration. In this paper, we investigate autophagosome dynamics in primary dorsal root ganglion neurons. Autophagosome biogenesis occurs distally in a constitutive process at the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283992/ https://ncbi.nlm.nih.gov/pubmed/22331844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106120 |
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