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Direct molecular interactions between HMGB1 and TP53 in colorectal cancer
Tumorigenesis and the efficacy of cancer therapeutics are both defined by the balance between autophagy and apoptosis. High-mobility group box 1 (HMGB1) is a DNA chaperone and extracellular damage-associated molecular pattern molecule (DAMP) with pro-autophagic activity. TP53/p53 plays a transcripti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378423/ https://ncbi.nlm.nih.gov/pubmed/22647615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19891 |
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