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p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

The balance between apoptosis (“programmed cell death”) and autophagy (“programmed cell survival”) is important in tumor development and response to therapy. Here we show that HMGB1 and p53 form a complex which regulates the balance between tumor cell death and survival. We demonstrate that knockout...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Livesey, Kristen M., Kang, Rui, Vernon, Philip, Buchser, William, Loughran, Patricia, Watkins, Simon C., Zhang, Lin, Manfredi, James J., Zeh, Herbert J., Li, Luyuan, Lotze, Michael T., Tang, Daolin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417120/
https://ncbi.nlm.nih.gov/pubmed/22345153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2291
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