p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

The balance between apoptosis (“programmed cell death”) and autophagy (“programmed cell survival”) is important in tumor development and response to therapy. Here we show that HMGB1 and p53 form a complex which regulates the balance between tumor cell death and survival. We demonstrate that knockout...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Livesey, Kristen M., Kang, Rui, Vernon, Philip, Buchser, William, Loughran, Patricia, Watkins, Simon C., Zhang, Lin, Manfredi, James J., Zeh, Herbert J., Li, Luyuan, Lotze, Michael T., Tang, Daolin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417120/
https://ncbi.nlm.nih.gov/pubmed/22345153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2291
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