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p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

The balance between apoptosis (“programmed cell death”) and autophagy (“programmed cell survival”) is important in tumor development and response to therapy. Here we show that HMGB1 and p53 form a complex which regulates the balance between tumor cell death and survival. We demonstrate that knockout...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Livesey, Kristen M., Kang, Rui, Vernon, Philip, Buchser, William, Loughran, Patricia, Watkins, Simon C., Zhang, Lin, Manfredi, James J., Zeh, Herbert J., Li, Luyuan, Lotze, Michael T., Tang, Daolin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417120/
https://ncbi.nlm.nih.gov/pubmed/22345153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2291
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