p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

The balance between apoptosis (“programmed cell death”) and autophagy (“programmed cell survival”) is important in tumor development and response to therapy. Here we show that HMGB1 and p53 form a complex which regulates the balance between tumor cell death and survival. We demonstrate that knockout...

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Detalhes bibliográficos
Main Authors: Livesey, Kristen M., Kang, Rui, Vernon, Philip, Buchser, William, Loughran, Patricia, Watkins, Simon C., Zhang, Lin, Manfredi, James J., Zeh, Herbert J., Li, Luyuan, Lotze, Michael T., Tang, Daolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417120/
https://ncbi.nlm.nih.gov/pubmed/22345153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2291
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