p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

The balance between apoptosis (“programmed cell death”) and autophagy (“programmed cell survival”) is important in tumor development and response to therapy. Here we show that HMGB1 and p53 form a complex which regulates the balance between tumor cell death and survival. We demonstrate that knockout...

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Détails bibliographiques
Auteurs principaux: Livesey, Kristen M., Kang, Rui, Vernon, Philip, Buchser, William, Loughran, Patricia, Watkins, Simon C., Zhang, Lin, Manfredi, James J., Zeh, Herbert J., Li, Luyuan, Lotze, Michael T., Tang, Daolin
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417120/
https://ncbi.nlm.nih.gov/pubmed/22345153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2291
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