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HMGB1 in Cancer: Good, Bad, or Both?

Forty years ago, high mobility group box 1 (HMGB1) was discovered in calf thymus and named according to its electrophoretic mobility in polyacrylamide gels. Now, we know that HMGB1 performs dual functions. Inside the cell, HMGB1 is a highly conserved chromosomal protein acting as a DNA chaperone. Ou...

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Detalhes bibliográficos
Main Authors: Kang, Rui, Zhang, Qiuhong, Zeh, Herbert J., Lotze, Michael T., Tang, Daolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732559/
https://ncbi.nlm.nih.gov/pubmed/23723299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0495
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