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HMGB1 in Cancer: Good, Bad, or Both?
Forty years ago, high mobility group box 1 (HMGB1) was discovered in calf thymus and named according to its electrophoretic mobility in polyacrylamide gels. Now, we know that HMGB1 performs dual functions. Inside the cell, HMGB1 is a highly conserved chromosomal protein acting as a DNA chaperone. Ou...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2013
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732559/ https://ncbi.nlm.nih.gov/pubmed/23723299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0495 |
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