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Direct molecular interactions between HMGB1 and TP53 in colorectal cancer

Tumorigenesis and the efficacy of cancer therapeutics are both defined by the balance between autophagy and apoptosis. High-mobility group box 1 (HMGB1) is a DNA chaperone and extracellular damage-associated molecular pattern molecule (DAMP) with pro-autophagic activity. TP53/p53 plays a transcripti...

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Bibliografische gegevens
Hoofdauteurs: Livesey, Kristen M., Kang, Rui, Zeh, Herbert J., Lotze, Michael T., Tang, Daolin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378423/
https://ncbi.nlm.nih.gov/pubmed/22647615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19891
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