Alpha-synuclein aggregation involves a bafilomycin A(1)-sensitive autophagy pathway

Synucleinopathies like Parkinson disease and dementia with Lewy bodies (DLB) are characterized by α-synuclein aggregates within neurons (Lewy bodies) and their processes (Lewy neurites). Whereas α-synuclein has been genetically linked to the disease process, the pathological relevance of α-synuclein...

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Detalhes bibliográficos
Main Authors: Klucken, Jochen, Poehler, Anne-Maria, Ebrahimi-Fakhari, Darius, Schneider, Jacqueline, Nuber, Silke, Rockenstein, Edward, Schlötzer-Schrehardt, Ursula, Hyman, Bradley T., McLean, Pamela J., Masliah, Eliezer, Winkler, Juergen
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378419/
https://ncbi.nlm.nih.gov/pubmed/22647715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19371
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