Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(−)c-Kit(+) innate cell population

Interleukin-25 (IL-25 or IL-17E), a member of the structurally related IL-17 family, functions as an important mediator of T helper 2 cell-type (type 2) responses. We examined the cell-type specific role of IL-25-induced Act1-mediated signaling in protective immunity against helminth infection. Targ...

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Main Authors: Kang, Zizhen, Swaidani, Shadi, Yin, Weiguo, Wang, Chenhui, Barlow, Jillian L., Gulen, Muhammet Fatih, Bulek, Katarzyna, Do, Jeong-su, Aronica, Mark, McKenzie, Andrew N. J., Min, Booki, Li, Xiaoxia
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376903/
https://ncbi.nlm.nih.gov/pubmed/22608496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.021
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