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The essential role of SIGIRR/TIR8 in regulation of Th2 immune response

A novel cytokine IL-33, an IL-1 family member, signals via ST2 receptor and promotes T helper type 2 (Th2) responses, through the activation of NFκB and MAP kinases. Previous studies reported that SIGIRR (single immunoglobulin IL-1R-related molecule)/TIR8 (Toll IL-1R8) acts as negative regulator for...

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Main Authors: Bulek, Katarzyna, Swaidani, Shadi, Qin, Jinzhong, Lu, Yi, Gulen, Muhammet F., Herjan, Tomasz, Min, Booki, Kastelein, Robert A., Aronica, Mark, Kosz-Vnenchak, Magdalena, Li, Xiaoxia
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891188/
https://ncbi.nlm.nih.gov/pubmed/19234154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802729
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