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The essential role of SIGIRR/TIR8 in regulation of Th2 immune response
A novel cytokine IL-33, an IL-1 family member, signals via ST2 receptor and promotes T helper type 2 (Th2) responses, through the activation of NFκB and MAP kinases. Previous studies reported that SIGIRR (single immunoglobulin IL-1R-related molecule)/TIR8 (Toll IL-1R8) acts as negative regulator for...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891188/ https://ncbi.nlm.nih.gov/pubmed/19234154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802729 |
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