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T cell-derived Act1 is necessary for IL-25-mediated Th2 responses and allergic airway inflammation()
The cellular and molecular mechanisms driven by IL-25 and its cognate receptor IL-17RB necessary for the promotion of T helper type 2 (Th2) mediating pathogenic pulmonary inflammation remain to be defined. We have previously reported the critical role of the U-box-type E3 ubiquitin ligase Act1 (1),...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666175/ https://ncbi.nlm.nih.gov/pubmed/21856933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002790 |
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