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Adaptive Isotonic Estimation of the Minimum Effective and Peak Doses in the Presence of Covariates
We consider a problem of estimating the minimum effective and peak doses in the presence of covariates. We propose a sequential strategy for subject assignment that includes an adaptive randomization component to balance the allocation to placebo and active doses with respect to covariates. We concl...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375738/ https://ncbi.nlm.nih.gov/pubmed/22711972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jspi.2012.01.024 |
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