Prevention of Premature Fusion of Calvarial Suture in GLI-Kruppel Family Member 3 (Gli3)-deficient Mice by Removing One Allele of Runt-related Transcription Factor 2 (Runx2)

Mutations in the gene encoding the zinc finger transcription factor GLI3 (GLI-Kruppel family member 3) have been identified in patients with Grieg cephalopolysyndactyly syndrome in which premature fusion of calvarial suture (craniosynostosis) is an infrequent but important feature. Here, we show tha...

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Autores principales: Tanimoto, Yukiho, Veistinen, Lotta, Alakurtti, Kirsi, Takatalo, Maarit, Rice, David P. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375564/
https://ncbi.nlm.nih.gov/pubmed/22547067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362145
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